1) Theanine, a specific glutamate derivative in green tea, reduces the adverse reactions of doxorubicin by changing the glutathione level. / Sugiyama, Tomomi; Sadzuka, Yasuyuki ( Cancer Letters , 2004 , 212(2) , 177 )

2) Possible involvement of group I mGluRs in neuroprotective effect of theanine. / Nagasawa, Kazuki; Aoki, Hiromitsu; Yasuda, Eri; Nagai, Katsuhito; Shimohama, Shun; Fujimoto, Sadaki ( Biochemical & Biophysical Research Communications , 2004 , 320(1) , 116 )

3) Neuroprotective effect of ¥ã-glutamylethylamide (theanine) on cerebral infarction in mice / Nobuaki Egashira; ( Neuroscience Letters , 2004 , 363(1) , 58-61 )

4) L-Theanine / ( Bio industry , 2004 , 21(2) , 84-86 )

5) Anti-obesity Effects of Three Major Components of Green Tea, Catechins, Caffeine and Theanine, in Mice / Zheng,
G.; Sayama, K.; Okubo, T.; Juneja, L. R. ( IN VIVO -ATHENS- , 2004 , 18(1) , 55 )


6) Antigens in tea-beverage prime human V¥ã 2Vdelta 2 T cells in vitro and in vivo for memory and nonmemory antibacterial cytokine responses / Arati B Kamath; Lisheng Wang; Hiranmoy Das; Lin Li; Vernon N Reinhold; Jack F Bukowski; ( Proceedings of the National Academy of Sciences of the United States of America , 2003 , 100(10) , 6009-6014 )

7) Green Tea Catechins and L-Theanine in Integrative Cancer Care: A Review of the Research / Huber, L.; ( ALTERNATIVE AND COMPLEMENTARY THERAPIES , 2003 , 9(6) , 294 )

8) Theanine and glutamate transporter inhibitors enhance the antitumor efficacy of chemotherapeutic agents. / Sugiyama, Tomomi; ( BBA - Reviews on Cancer , 2003 , 1653(2) , 47 )

9) Progress in studies of theanine / ( NATURAL PRODUCT RESEARCH AND DEVELOPMENT , 2003 , 15(4) , 369 )

10) Inhibition by Theanine of Binding of [^3H]AMPA, [^3H]Kainate, and [^3H]MDL 105,519 to Glutamate Receptors / ( BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY , 2002 , 66(12) , 2683 )

11) Enzymatic production of theanine, an "umami" component of tea / Kumagai, H.; ( ENZYME AND MICROBIAL TECHNOLOGY , 2002 , 31() , 884-889 )

12) Glutamate Transporter Mediated Increase of Antitumor Activity by Theanine, an Amino Acid in Green Tea / Sadzuka, Y.; Yamashita, Y.; Kishimoto, S.; Fukushima, S.; Takeuchi, Y.; Sonobe, T.; ( JOURNAL- PHARMACEUTICAL SOCIETY OF JAPAN , 2002 , 122() , 995-1000 )

13) The preparation and application of theanine / Xu, Y.; Chen, X.-b.; Xiao, W.-x.; Chen, X.-b.; Xiao, W.-x ( NATURAL PRODUCT RESEARCH AND DEVELOPMENT , 2002 , 14() , 77-80 )

14) Effects of Dietary Powdered Green Tea and Theanine on Tumor Growth and Endogenous Hyperlipidemia in Hepatoma-bearing Rats / Zhang, G.; Miura, Y.; Yagasaki, K.; ( BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY , 2002 , 66(4) , 711-716 )

15) Synthesis of L-Theanine / Li, C.-r.; ( FINE CHEMICALS -DALIAN- , 2001 , 18() , 223-224 )

16) Inhibition of glutamate transporter by theanine enhances the therapeutic efficacy of doxorubicin / Sugiyama, T.; Sadzuka, Y.; Tanaka, K.; Sonobe, T.; ( TOXICOLOGY LETTERS , 2001 , 121(2) , 89 - 96 )

17) Inhibitory effects of theanine and sera from theanine-fed rats on receptor-mediated cancer cell invasion beneath mesothelial-cell monolayers / Guoying Zhang; Yutaka Miura; Kazumi Yagasaki (Department of Applied Biological Science, Tokyo Noko University, Saiwaicho 3-5-8, Fuchu, Tokyo 183-8509, Japan); ( CYTOTECHNOLOGY , 2001 , 36(1) , 195-200 )

18) Inhibitory effects of theanine and sera from theanine-fed rats on receptor-mediated cancer cell invasion beneath mesothelial-cell monolayers / Zhang, G.; Miura, Y.; Yagasaki, K. ( Japanese Association for Animal Cell Technology; Animal cell technology for creation of new era , 2000; Nov , 2001; VOL 36; NOS 1-3 , 195-200 )

19) Protective effect of g-glutamylethylamide (theanine) on ischemic delayed neuronal death in gerbils / Kakuda, T; Yanase, H ; Utsunomiya, K ; Nozawa, A ; Unno, T ; Kataoka, K; ; ( NEUROSCIENCE LETTERS ,2000 , 289(3) , 4 )

20) Effect of theanine, r-glutamylethylamide, on brain monoamines, striatal dopamine release and some kinds of behavior in rats / Yokogoshi, H.; Terashima, T.; ( NUTRITION -BURBANK THEN SYRACUSE- , 2000 , 16(9) , 776-777 )

21) Improvement of idarubicin induced antitumor activity and bone marrow suppression by theanine, a component of tea / Sadzuka, Y.; Sugiyama, T.; Sonobe, T.; ( CANCER LETTERS , 2000 , 158(2) , 119-124 )

22) Inhibiting Effects of Theanine on Caffeine Stimulation Evaluated by EEG in the Rat / KAKUDA, T.; NOZAWA, A.; UNNO, T.; OKAMURA, N.; OKAI, O.; ( BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY , 2000 , 64() , 287-293 )

23) Liver Injury-preventive Effect of Tea Theanine in Rats. / He, P.; Watanabe, N.; ( Journal of Food Science , 2000 , 65(1) , 30 )

24) Erratum: L-theanine - a unique amino acid of green tea and its relaxation effect in humans (Trends in Food Science and Technology 10, 6-7) / Juneja_L_R; ( Trends in Food Science and Technology , 2000 , 10(8) , 278 )

25) Corrigendum: L-theanine - A unique amino acid of green tea and its relaxation effect in humans (Trends in Food Science and Technology (1999) 10 (6-7) (199-204) PII: S0924224499000448) / Juneja_L_R; Chu_D_-C; Okubo_T; Nagato_Y; Yokogoshi_H; ( Trends in Food Science and Technology , 1999 , 10(12) , 425 )

26) Human gamma delta T cells recognize alkylamines derived from microbes, edible plants, and tea: implications for innate immunity / Bukowski JF, et al.; (Immunity, 1999 , Jul; 11(1), 57-65 )

27) Combination of Theanine with Doxorubicin Inhibits Hepatic Metastasis of M5076 Ovarian Sarcoma / Sugiyama, T.; Sadzuka, Y.; ( CLINICAL CANCER RESEARCH , 1999 , 5(2) , 413-416 )

28) Effects of L-Theanine on the Release of alpha-Brain Waves in Human Volunteers/ Sugimoto, S.; ( NIPPON NOGEIKAGAKU KAISHI , 1998 , 72() , 153-160 )

29) Theanine-induced Reduction of Brain Serotonin Concentration in Rats / Yokogoshi, H.; Mochlzuki, M.; Saltoh, K.; ( BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY , 1998 , 62(4) , 816 )

30) Effect of Theanine, r-Glutamylethylamide, on Brain Monoamines and Striatal Dopamine Release in Conscious Rats / Yokogoshi, H.; Kobayashi, M.; Mochizuki, M.; Terashima, T.; ( NEUROCHEMICAL RESEARCH , 1998 , 23(5) , 667 )

31) Green tea component, theanine enhances the antitumor activity of adriamycin against sensitive P388 leukemia and resistant P388-ADR./ Sugiyama T, et al; ( Proceedings of the American Association for Cancer Research Annual Meeting. 1998, Vol. 39, 528)

32) Theanine, a major flavorous amino acid in green tea leaves, inhibits glutamate-induced neurotoxicity on cultured rat cerebral cortical neurons. /Nozawa, A. et al; (Society for Neuroscience Abstracts. 1998, Vol. 24, No. 1-2, p. 978)

33) Hypotensive effect of gamma-glutamylethylamide in spontaneously hypertensive rats. / Yokogoshi H, et al; (Life Sci. 1998; 62(12): 1065-8)

34) Varietal Differences in the Total and Enantiomeric Composition of Theanine in Tea / Ekborg-Ott, K. H.; Taylor, A.; Armstrong, D. W.; ( JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY , 1997 , 45(2) , 353 )

35) The effects of theanine, as a novel biochemical modulator, on the antitumor activity of adriamycin. / Sadzuka Y, et al; (Cancer Lett. 1996 Aug 2;105(2): 203-9)

36) Reduction effect of theanine on blood pressure and brain 5-hydroxyindoles in spontaneously hypertensive rats / Yokogoshi, Hidehiko ; Sagesaka, Yuko M.; Kato, Yukiko ; ( "Bioscience, Biotechnology, and Biochemistry" , 1995 , 59(4) , )

37) Theanine a glutamate analog, stimulates NMDA-receptors by suppresses excitatory effect of caffeine in cortical neurons. / Nozawa, A. et al; (Society for Neuroscience Abstracts. 1995, Vol. 21, No. 1-3, p. 835)

38) Pharmacological effect of theanine. / Sagesaka Y, et al; (Proceedings of the International Symposium on Tea Science, August 26-29, 1991, 362-364 )

39) Metabolism of L-theanine in tea leaves. / Tsushida, T; (Japan Agricultural Research Quarterly. 1987, Vol. 21, No. 1 p.42-46)

40) Effect of theanine on norepinephrine and serotonin levels in rat brain./ Kimura R, et al; (Chem Pharm Bull. 1986 Jul;34(7): 3053-7)

41) Theanine as a glutamic antagonist at a crayfish neuromuscular junction./ Shinozaki H, et al; (Brain Res. 1978. Jul 28;151(1):215-9)

42) Influence of alkylamides of glutamic acid and related compounds on the central nervous system. III. Effect of theanine on spontaneous activity of mice./ Kimura R, et al; (Yakugaku Zasshi. 1975 Jul; 95(7):892-5)

 
 
 
 
 

 
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Green tea amino acid L-theanine